This paper presents the implementation Problem-Based Learning (PBL) design in entrepreneurship and innovation management education, with a focus on enhancing students' innovative behavior and entrepreneurial orientation through the usage of different digital tools. A survey was conducted among 118 students from Germany, the Netherlands, and Poland. The findings of the study demonstrate that engaging in PBL activities has a positive impact on students’ digital tool usage, innovative behavior, and entrepreneurial orientation. Additionally, the results provide support for the full mediating role of students’ innovative behavior in the relationship between PBL activities and students’ entrepreneurial orientation. As a result, based on this research, we encourage Higher Education Institutions to incorporate digital tool usage into PBL open-source educational resources, thereby integrating effective skill sets into innovation and entrepreneurship education