In dynamic and competitive environment, the importance of innovation is accepted as a necessary ingredients for firms to create value and sustain competitive advantage. However, very little empirical research has specifically addressed to what extent different kinds of innovation rely on specific knowledge management processes and entrepreneurial orientation. The objective of this study is to identify the different types of innovation that are predominant in companies, and how to facilitate different types of innovation activities. A questionnaire survey was conducted and 169 valid replies were received. This research analyzes the relationship among knowledge management processes, as well as entrepreneurial orientation and different types of innovation. The results from an empirical survey study reveal that organizations facilitate different types of innovation (i.e., administrative versus technical innovation) through entrepreneurial orientation and knowledge management process (i.e., knowledge acquisition, knowledge sharing and knowledge application). The results also show that the partial mediating role of knowledge management processes in the relationship between entrepreneurial orientation and different types of innovation.